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2024-10-17

SCIENCE AND ENGINEERING

Genetics: A Journey from Personal Experience

Genetics: A Journey from Personal Experience

I'll tell it to you straight: genetics is everything. And no, I'm not exaggerating. I've had the good fortune - or misfortune, depending on how you see it - to have genetics touch me more closely than I would have liked. It's a science that literally determines who we are, how we look, how we think and even what diseases we might have in the future. Too much? Maybe. But it's the truth.

I'll tell you from my experience, because I'm not one to repeat what I heard on TV or read around. I experienced this myself, firsthand. And believe me, when you get really into genetics, you never see the world the same way again.

Let's start with the basics. genetics is the study of genes, those microscopic fragments that carry the instructions for life. Every living thing has genes, whether it's a human being, a plant or that pesky mosquito that bit you last night. And these genes are in the DNA, that sort of spiral staircase that carries all the code needed to build a body, a mind and, yes, even a personality.

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Now, modern genetics began to take shape in the 19th century, thanks to a monk named Gregor Mendel, who devoted himself to doing experiments with pea plants (I swear, I'm not making this up). This man discovered the basic laws of heredity, those that tell us why you inherit your mother's eyes but your father's temperament. What Mendel did was open Pandora's box: now we could begin to understand why we are the way we are.

DNA: That Code That Defines Us

Here comes the good stuff. DNA, which is the basis of everything, is nothing more than a long sequence of four bases: adenine, guanine, cytosine and thymine. Imagine you have four letters with which you have to write a book that not only tells your story, but also tells how your body is going to function. And even though there are only four letters, combined in trillions of possible ways, they can do mind-blowing things.

Genes are like chapters in this book. Some are shorter, some are longer, but all are important. A specific gene tells your body how to make a protein, and those proteins are basically the building blocks of everything you are. From the color of your skin to the shape of your fingernails, it's all encoded in DNA.

And here's where things get interesting, because genetics doesn't just tell you what you look like physically. It also affects how you function on the inside, from your metabolism to your predisposition to disease. Did you know that there are genes that predict whether you will get cancer or heart disease? I found this out from my own experience, when a close family member had to have a genetic test to detect a possible predisposition to breast cancer. It was an experience that made me realize how powerful - and sometimes frightening - genetics can be.

What Do Genes Determine and What Don't?

One of the most fascinating concepts I've learned about genetics is the difference between genotype and phenotype. Genotype is basically the complete set of genes you have. Everything you could be. Phenotype, on the other hand, is who you really are, i.e., how those genes interact with the environment to shape your physical appearance, behavior and health.

And you know what? Although your genes determine a lot, they don't determine everything. Your environment, your experiences, the choices you make, all those factors also play a crucial role in who you are. It's like your genes are the basic rules of a game, but you decide how to play it.

And this is where things get even crazier. There's something called epigenetics, which is basically the study of how the environment can turn certain genes on or off. So even if you have a genetic predisposition to something, like diabetes, if you watch your diet and exercise, you could prevent that gene from being turned on. Crazy, right!

Revolution in Medicine

If I tell you that genetics has revolutionized medicine, that's an understatement. We are talking about the fact that we can now sequence the entire human genome, which allows us to know much more about how to prevent and treat diseases. Today, thanks to genetic tests, you can know if you have a predisposition to diseases such as Alzheimer's or cancer, long before the first symptoms appear.

I remember when a good friend of mine, after taking a genetic test, discovered that she had a high probability of developing breast cancer. That information led her to make a drastic decision: she opted for a preventive mastectomy. And here's the amazing thing about genetics: it gives you the ability to take control of your destiny, or at least try.

But it's not all so pretty. There is a huge debate about the ethical aspects of genetics. Imagine if insurers could have access to your genetic information and know that you are prone to certain diseases. They could, without further ado, raise your insurance premiums. Or worse, deny you coverage. Scary, isn't it?

The Future of Genetics: What Awaits Us?

I don't want to lie to you, we're only scratching the surface of what genetics can do. What seems like science fiction today, such as editing genes with tools like CRISPR, could become an everyday occurrence in a few decades. There is already talk of the possibility of "curing" genetic diseases before a person is born, or even improving certain characteristics. Yes, I'm talking about "designer" babies.

Personally, I have mixed feelings about this. On the one hand, the possibility of eliminating inherited diseases is an amazing thing. But where do we draw the line - what if we start editing genes to make our children taller, smarter, or even more attractive? Genetics has immense power, but with that power comes great responsibility.

Conclusion

Genetics is like a box of surprises. It gives us answers to questions we never thought to ask, and at the same time leaves us with more questions than we can solve. I have learned, over the years, that our genes are only part of the equation. The rest is built by us with our decisions, our environment and our experiences.

So, my friend, if you ever wonder why you are the way you are, look inward. Your genes have a lot to tell you, but remember, you also have something to say to them.

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